Question

Akatsuki Dawn

求解3.79！！

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Dofq for unilqferqgl cqses

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外 39       2       66

Total             63          65 128

Dofoq for bilqfTerql cgqses

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Antibiotic 0             1 Total
3轉3           88
99           29          62
Total              70           02 0

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|   |     中         88
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Total              70           8$0 “150

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Doftq for +TofTql cqses

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3.78 ifthe population tested is representative ofthe general
population, then what are the and Pv' using this test?

Otolaryngology

The data set in Table 3.12 is based on 214 children with
acute otitis media (otitis media with effusion or OME) who
participated in a randomized clinical trial [13]. Each child
had OME at the beginning ofthe study in either one (unilat-
eral cases) or both (bilateral cases) ears and was randomly
assigned to receive a 14-day course of one oftwo antibiot-
ics, either cefaclor (CEF) or amoxicillin (AMO). The data
here concern the 203 children whose middle-ear status
was determined during a 14-day follow-up visit. The data

20Om ll in Table 3.12 are presented in data set EAR.DAT (at www

,cengagebrain.com)-

人3  V3.79 Does there seem to be any difference in the effect of

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ithe

 

the antibiotics on clearance of otitis media? Express your
results in terms of re/afve //sk (RAR). Consider separate
analyses for unilateral and bilateral cases. Also consider an
analysis combining the two types of cases.

3.80 The investigators recorded the ages of the children
because they felt this might be an important factor in de-
termining outcome. Were they right? Try to express your
results in terms of RR擴

3.81 While controlling for age, propose an analysis com-
paring the effectiveness ofthe two antibiotics. Express your
results in terms of AR

3.82 Another issue in this trial is the possible dependence
between ears for the bilateral cases. Comment on this issue
based on the data collected.

The concept ofarandomized clinicaltrialis discussed more
completely in Chapter 6. The analysis of contingency-table

TABLE 3.12 Format for EAR,DAT

 

Column 。”Variable                                      Format or code

 

1-3          ID
有             人learance bv 14 daves       和1 三ves/0 二no