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生物 高校生

黒く囲んでる320は、どう計算したら320になるのか教えて欲しいです😓

参考抗体の多様性 多様な抗原に対しては,その抗原それぞれに対応する可変部をもった抗体 が必要となる。抗体の遺伝子の数は必要な抗体の種類よりきわめて少ないが、 抗体の可変部のアミノ酸配列を指定している遺伝子が次のようなしくみに よって多様化されることで, 多種類の抗体がつくられている。 同じ個体の体細胞は, 同じゲノムをもっている。しかし, B細胞とT細胞 では,分化する際に, 特定の遺伝子に関して遺伝子の“連結” による"再編成" が行われる。成熟したB細胞は, 1個につき1種類の可変部をもった免疫グ ロブリンをつくるが,例えばヒトの場合, 未分化なB細胞にある免疫グロブ リンのH鎖の遺伝子領域の中には, 可変部の遺伝子である V遺伝子が 40種 類,D遺伝子が 25 種類,J遺伝子が6種類, そして定常部の遺伝子が並んで 5 variable (可変) diversity (多様) いる。B細胞が成熟する間に,V, D, J遺伝子からそれぞれ1つずつ選ばれ て“連結”され, “再編成”される(図I)。すると, このH鎖の可変部の遺 joining (接続) 伝子の組み合わせは 40 × 25 ×6=6000 通りになる。一方, L鎖の可変部に はH鎖とは異なるV遺伝子とJ遺伝子があり, 同様の“連結” と“再編成” によって320通りの組み合わせが生じる。そのため, H鎖とL鎖とからなる 抗体の可変部の遺伝子の組み合わせは, 192万通りにもなる。 このしくみは,1977年に利根川進によって解明され, この功績によって, 利根川は 1987 年にノーベル生理学·医学賞を受賞した。 つ H鎖の遺伝子 V断片 D断片 J断片 定常部 未分化なB細胞 分化 V1 V2 v39 連結·再編成された遺伝子 成熟したB細胞 合成 |V1 V2 函J5-06- 免疫グロブリン V2 DSJ5 H鎖 免疫グロブリン 本合成 成熟したB細胞 連結·再編成 J-ロー された遺伝子 L鎖 L鎖 本分化 未分化なB細胞 H--■■ ロ-ロ 定常部 L鎖の遺伝子 V断片 J断片 免疫グロプリン D図I 抗体の多様性のしくみ

未解決 回答数: 1
英語 高校生

英語に自信がある人回答づくりお願いします! ※書き込みは気にしないでください。 これプラス、問題に続きがあって、 問5 本文には、実物の動物を見ることによって人々がより深く理解できることが3つ書かれています。それらを日本語で答えなさい。 問6 本文には、動物園... 続きを読む

第4問 次の英文を読んで、 設問に答えなさい。①~6は段落番号です。 黒体 6) のIn my view, (1)it_is perfectly possible for many species of animals living in gon.. ie parks to have a quality of life as high as, or higher than, in the wild. 'Animals in ood z0os get a varied and high-quality diet with all the supplements required. and anv 1pesses they might have will be treated.Their movement might be somewhat restricted. mt they have a safe environment in which to live, and they are spared bullying and social 神年 predators*2 or the irritation and pain of parasites or injuries. The average captive animal racism*1 by others of their kind. They do not suffer from the threat or stress of will have a greater life expectancy compared with its wild counterpart, and will not die of drought, of starvation or in the jaws of a predator. Alot of very nasty things happen to truly wild' animals that simply don't happen in good zoos, and to view a life that is 'free' as 術保者一 one that is automatically ‘good' is, I think, an error. Furthermore, zoos serve several key purposes. の Firstly, zoos aid conservation. Colossal numbers of species are becoming extinct across the world, and many more are increasingly threatened and therefore risk extinction. Moreover, some of these collapses have been sudden, dramatic and unexpected, or were simply discovered very late in the day. Aspecies protected in captivity can be bred up to provide a reservoir*3 population against a population crash or extinction in the wild. A good number of species only exist in captivity, with many ofthese livinginzoos. Stillmore only exist in the wildbecause they have been reintroduced from zoos, or have wild populations that have been1o0osted by captive bred animals Without (2these efforts there would be fewer species alive today. Although reintroduction successes are few and far between*4, the numbers are increasing, and the very fact that species have been saved or reintroduced as a result of captive breeding proves the value of such initiatives. ③ Zoos alsoprovide education. Many children and adults, especially those in cities, will never see a wild animal beyond a fox or pigeon. While it is true that television documentaries are becoming ever more detailed and impressive, and many natural history specimens are on display in museums, there really is nothing to compare with seeinga living creature in the flesh*5, hearing it, smelling it, watching what it does and having the time to absorb details. That alone will bring a greater understanding and perspective to many, and hopefully give them a greater appreciation for wildlife, conservation efforts and how they can contribute. ④ Inaddition to this, there isalsothe education that cantake place in Z0Osthrough signs, talks and presentations which directly communicate information to visitors about the animals they are seeing and their place in the world. This was an area where zoos used to be lacking, but they are now increasingly sophisticated in their communication and 8.

回答募集中 回答数: 0
英語 高校生

英語に自信がある人回答づくりお願いします! ※書き込みは気にしないでください。 これプラス、問題に続きがあって、 問5 本文には、実物の動物を見ることによって人々がより深く理解できることが3つ書かれています。それらを日本語で答えなさい。 問6 本文には、動物園... 続きを読む

第4問 次の英文を読んで、 設問に答えなさい。①~6は段落番号です。 黒体 6) のIn my view, (1)it_is perfectly possible for many species of animals living in gon.. ie parks to have a quality of life as high as, or higher than, in the wild. 'Animals in ood z0os get a varied and high-quality diet with all the supplements required. and anv 1pesses they might have will be treated.Their movement might be somewhat restricted. mt they have a safe environment in which to live, and they are spared bullying and social 神年 predators*2 or the irritation and pain of parasites or injuries. The average captive animal racism*1 by others of their kind. They do not suffer from the threat or stress of will have a greater life expectancy compared with its wild counterpart, and will not die of drought, of starvation or in the jaws of a predator. Alot of very nasty things happen to truly wild' animals that simply don't happen in good zoos, and to view a life that is 'free' as 術保者一 one that is automatically ‘good' is, I think, an error. Furthermore, zoos serve several key purposes. の Firstly, zoos aid conservation. Colossal numbers of species are becoming extinct across the world, and many more are increasingly threatened and therefore risk extinction. Moreover, some of these collapses have been sudden, dramatic and unexpected, or were simply discovered very late in the day. Aspecies protected in captivity can be bred up to provide a reservoir*3 population against a population crash or extinction in the wild. A good number of species only exist in captivity, with many ofthese livinginzoos. Stillmore only exist in the wildbecause they have been reintroduced from zoos, or have wild populations that have been1o0osted by captive bred animals Without (2these efforts there would be fewer species alive today. Although reintroduction successes are few and far between*4, the numbers are increasing, and the very fact that species have been saved or reintroduced as a result of captive breeding proves the value of such initiatives. ③ Zoos alsoprovide education. Many children and adults, especially those in cities, will never see a wild animal beyond a fox or pigeon. While it is true that television documentaries are becoming ever more detailed and impressive, and many natural history specimens are on display in museums, there really is nothing to compare with seeinga living creature in the flesh*5, hearing it, smelling it, watching what it does and having the time to absorb details. That alone will bring a greater understanding and perspective to many, and hopefully give them a greater appreciation for wildlife, conservation efforts and how they can contribute. ④ Inaddition to this, there isalsothe education that cantake place in Z0Osthrough signs, talks and presentations which directly communicate information to visitors about the animals they are seeing and their place in the world. This was an area where zoos used to be lacking, but they are now increasingly sophisticated in their communication and 8.

回答募集中 回答数: 0
英語 高校生

英語に自信がある人回答づくりお願いします! ※書き込みは気にしないでください。 これプラス、問題に続きがあって、 問5 本文には、実物の動物を見ることによって人々がより深く理解できることが3つ書かれています。それらを日本語で答えなさい。 問6 本文には、動物園... 続きを読む

第4問 次の英文を読んで、 設問に答えなさい。①~6は段落番号です。 黒体 6) のIn my view, (1)it_is perfectly possible for many species of animals living in gon.. ie parks to have a quality of life as high as, or higher than, in the wild. 'Animals in ood z0os get a varied and high-quality diet with all the supplements required. and anv 1pesses they might have will be treated.Their movement might be somewhat restricted. mt they have a safe environment in which to live, and they are spared bullying and social 神年 predators*2 or the irritation and pain of parasites or injuries. The average captive animal racism*1 by others of their kind. They do not suffer from the threat or stress of will have a greater life expectancy compared with its wild counterpart, and will not die of drought, of starvation or in the jaws of a predator. Alot of very nasty things happen to truly wild' animals that simply don't happen in good zoos, and to view a life that is 'free' as 術保者一 one that is automatically ‘good' is, I think, an error. Furthermore, zoos serve several key purposes. の Firstly, zoos aid conservation. Colossal numbers of species are becoming extinct across the world, and many more are increasingly threatened and therefore risk extinction. Moreover, some of these collapses have been sudden, dramatic and unexpected, or were simply discovered very late in the day. Aspecies protected in captivity can be bred up to provide a reservoir*3 population against a population crash or extinction in the wild. A good number of species only exist in captivity, with many ofthese livinginzoos. Stillmore only exist in the wildbecause they have been reintroduced from zoos, or have wild populations that have been1o0osted by captive bred animals Without (2these efforts there would be fewer species alive today. Although reintroduction successes are few and far between*4, the numbers are increasing, and the very fact that species have been saved or reintroduced as a result of captive breeding proves the value of such initiatives. ③ Zoos alsoprovide education. Many children and adults, especially those in cities, will never see a wild animal beyond a fox or pigeon. While it is true that television documentaries are becoming ever more detailed and impressive, and many natural history specimens are on display in museums, there really is nothing to compare with seeinga living creature in the flesh*5, hearing it, smelling it, watching what it does and having the time to absorb details. That alone will bring a greater understanding and perspective to many, and hopefully give them a greater appreciation for wildlife, conservation efforts and how they can contribute. ④ Inaddition to this, there isalsothe education that cantake place in Z0Osthrough signs, talks and presentations which directly communicate information to visitors about the animals they are seeing and their place in the world. This was an area where zoos used to be lacking, but they are now increasingly sophisticated in their communication and 8.

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生物 高校生

遺伝子の再編成のとこです なんでL鎖が320通りなんでしょうか、??

多様な抗原に対レしては, その抗原それぞれに対応する可変部をもった抗体 が必要となる。抗体の遺伝子の数は必要な抗体の種類よりきわめて少ないが 抗体の可変部のアミノ酸配列を指定している遺伝子が次のようなしくみに よって多様化されることで, 多種類の抗体がつくられている。 同じ個体の体細胞は, 同じゲノムをもっている。 しかし, B 細胞と工細胞 では,分化する際に, 特定の遺伝子に関して遺伝子の “連結” による『 再編成? が行われる。成熟した B 細胞は, 1 個につき 1 種類の可変部をもった免疫グ ロブリンをつくるが, 例えばヒトの場合,未分化な B 細胞にある免疫グロプ リンの H鎖の遺伝子領域の中には, 可変部の遺伝子である 遺伝子が 40 竹 variable (可変) 類, の 遺倒子が 25 種類,/ 遺伝子が 6 種類 そして定常部の遺伝子が並んで いる。 B 細胞が成熱する問に。 の. 遺伝子からそれぞれ1つずつ選ばぼれ て“連結” され, “再編成”? される(図 [ )。すると, ごのHH鎖の可変部の遺 伝子の組み合わせは 40 X 25 X 6 = 6000 通りになる』二坊叶『 鎖の可変部に は H 鎖とは異なる遺伝子と/ 遺伝子があり, 同様の連結月と再編成/ によって 320 通りの組み合わせが生じる。そのため請還鎖る 鎖とからなる 抗体の可変部の遺伝子の組み合わせは, 192 亡通りIaもなる5 このしくみは, 1977 年に利根川進によっで解明され年との功績によって, 利根川は 1987 年にノーベル生理学 ・医学賞を受賞した。 H鎖の遺伝子 未分化なB細胞 ャ分化 成吾したB細胞 =給上 L鎖の遺伝了 | 〇図{ 抗体の多様性の ブロブプリン

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